Most people give themselves one injection in the hour before breakfast and another in the hour before dinner. Your second injection would still be in the hour before your dinner, as long as these meals are at least 6 hours apart. After 4 weeks, your doctor may increase your dosage to 10 mcg twice a day.
This will depend on how well your blood sugar levels respond to Byetta injections. Your doctor will decide what the best dosage is for you. Never use a double dose to make up for a missed dose.
A medication timer may be useful, too. Byetta is meant to be used as a long-term treatment. Byetta can cause mild or serious side effects. The following lists contain some of the key side effects that may occur while taking Byetta. These lists do not include all possible side effects. For more information on the possible side effects of Byetta, talk with your doctor or pharmacist.
They can give you tips on how to deal with any side effects that may be bothersome. Most of these side effects may go away within a few days or a couple of weeks. Call your doctor right away if you have serious side effects. You may wonder how often certain side effects occur with this drug , or whether certain side effects pertain to it.
As with most drugs, some people can have an allergic reaction after taking Byetta. Symptoms of a mild allergic reaction can include:. A more severe allergic reaction is rare but possible. Symptoms of a severe allergic reaction can include:.
Call your doctor right away if you have a severe allergic reaction to Byetta. However, mild and severe allergic reactions have been reported since the drug came on the market in This is called hypoglycemia. Talk to your doctor about what to do if you experience symptoms of hypoglycemia, which can include:.
Pancreatitis was not reported in clinical studies of Byetta. However, a few people using Byetta have experienced acute pancreatitis inflammation of the pancreas since the drug came on the market in Some of these cases were serious or fatal.
Call your doctor right away if you experience any symptoms of acute pancreatitis. Your doctor may tell you to stop using Byetta. Symptoms of acute pancreatitis can include:.
The weight loss side effect can be beneficial for people with type 2 diabetes. Weight loss is most likely caused by Byetta making you want to eat less. However, Byetta is not a weight loss drug and should not be used solely for this purpose. Weight gain was not reported with Byetta in these studies. Some people using Byetta experience diarrhea.
If you get diarrhea while using Byetta, talk with your doctor or pharmacist about how to manage it. Drink plenty of fluids to avoid getting dehydrated when your body loses more fluid than you drink. You may find that you feel nauseated when you first start using Byetta. Feelings of nausea tend to get better with time. Hair loss alopecia was not reported in clinical studies of Byetta. However, it has been reported by some people using Byetta since the drug was approved.
A literature review of safety issues with Byetta and other drugs in the same class did not find any association between pancreatic cancer and use of these drugs. However, the long-acting form of exenatide, which is the main drug in Byetta, does have such a warning.
This form of exenatide is available as the brand-name drug Bydureon. An FDA boxed warning is used to alert doctors and patients about potentially serious side effects that might be associated with a drug.
Bydureon has one because it was shown to cause thyroid cancer in some animals. However, results from animal studies do not necessarily apply to humans. The FDA has also issued boxed warnings about thyroid cancer for other medications in the same drug class as Byetta. These drugs are liraglutide Victoza , semaglutide Ozempic , albiglutide Tanzeum , and dulaglutide Trulicity.
These warnings are also based on animal studies. However, these drugs have not been shown to cause thyroid cancer in humans. This is because data needs to be collected over a very long period of time. As with all medications, the cost of Byetta can vary. To find current prices for Byetta in your area, check out GoodRx.
The cost you find on GoodRx. If you need financial support to pay for Byetta, or if you need help understanding your insurance coverage, help is available. AstraZeneca, the manufacturer of Byetta, offers a savings card called MySavingsRx, which can help lower the cost of Byetta.
To learn more, call or visit the program website. Other drugs are available for treating type 2 diabetes. Some may be a better fit for you than others. They can tell you about other medications that may work well for you. You may wonder how Byetta compares to other medications that are prescribed for similar uses. Here we look at how Byetta and Bydureon are alike and different.
Byetta and Bydureon are both FDA-approved to help control blood sugar levels in adults with type 2 diabetes. They are used along with a diet and exercise program. Both of these medications contain exenatide, so they work the same way in the body. Byetta is a short-acting form of the drug that wears off after a few hours.
Bydureon is a long-acting form of exenatide that works for a longer period. Byetta comes as a prefilled multidose injection pen. You give yourself an injection under your skin subcutaneous twice a day, before your main meals. Bydureon comes as a single-dose injection pen or a single-dose syringe. It also comes as a single-dose prefilled autoinjector called Bydureon BCise.
With all forms of Bydureon, you give yourself an injection under your skin once a week, on the same day each week. Byetta and Bydureon both contain exenatide. Therefore, both medications can cause very similar side effects. Int J Obes Lond. Epub Jan Exenatide has a pronounced effect on energy intake but not energy expenditure in non-diabetic subjects with obesity: A randomized, double-blind, placebo-controlled trial.
Epub Mar National Library of Medicine U. National Institutes of Health U. Department of Health and Human Services. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Weight Loss Obesity. Phase 3. Study Type :. Interventional Clinical Trial. Actual Enrollment :. Study Start Date :. Actual Primary Completion Date :. Actual Study Completion Date :. Active Comparator: Exenatide 10 micrograms subcutaneously twice.
Drug: Byetta exenatide Exenatide is an injectable medication Behavioral: Weight loss Because response to weight loss. Placebo Comparator: Placebo Twice daily.
I also had elevated liver enzymes that showed I had a fatty liver, which can lead to nonalcoholic steatohepatitis and liver failure. Now, my liver enzymes are normal. My blood pressure was never all that high. But it too has come down from over 80 to over All of my cholesterol levels are much better.
My total cholesterol has dropped from to , well within the normal range of under My LDL cholesterol dropped from to 93, below the recommended level of under My HDL cholesterol — the good stuff — was always far too low.
It has gone from 28 to 40, right at the recommended level. Now that my weight and blood glucose levels are under control, I feel at least 10 years younger. I have a whole lot more energy than I have had in years. My mood is much more positive. In my case, I don't expect to ever stop using Byetta or a forthcoming product in that category of drugs.
That's because nothing else has helped me control my voracious appetite. However, I have stopped using all other type 2 diabetes drugs. The biggest problem is that my waist size dropped from 56 inches to 40 inches.
That meant I had to buy a whole new wardrobe of slacks, shirts, and underwear. He writes at www. I knew how to eat low-glycemic food, but I ate to o much and exercised too little. GLP-1 agonists: Diabetes drugs and weight loss. Products and services. Are there any type 2 diabetes drugs that can help people lose weight and lower their blood sugar?
Are there side effects? Answer From M. Regina Castro, M. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information. Please try again. Something went wrong on our side, please try again. Show references American Diabetes Association. Standards of medical care in diabetes — Diabetes Care. Dungan K, et al. Glucagon-like peptide 1 receptor agonists for the treatment of type 2 diabetes mellitus.
Accessed April 10, Goldman L, et al. Diabetes mellitus. In: Goldman-Cecil Medicine. Elsevier; Accessed April 11, Hu M, et al.
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