Younis IR et al Stable isotope pharmacokinetic studies provide insight into effects of age, sex, and weight on levothyroxine metabolism. Thyroid — Epub Jan 2. PMID: Participants in this study were patients with hypothyroidism who were treated at Georgetown University Medical Center.
A total of 33 female and 8 male patients were included — 31 were younger and 10 were older than 60 years of age. They did not have any other major medical problem. It might help to keep the room cool and use a fan. You could also spray your face with cool water or sip cold or iced drinks. The flushing should go away after a few days. If you get unusual muscle ache, which is not from exercise or hard work, talk to your doctor.
You may need a blood test to find the cause. In rare cases, it's possible to have a serious allergic reaction anaphylaxis to levothyroxine. These are not all the side effects of levothyroxine. For a full list see the leaflet inside your medicines packet. It's important to carry on taking levothyroxine throughout your pregnancy. Having too low or too high levels of thyroid hormone in pregnancy can cause problems for you and your baby. You'll need to have regular blood tests during pregnancy to make sure you're on the right dose of levothyroxine for you and your baby.
Most women need to take a higher dose of levothyroxine than usual while they're pregnant. It's usually safe to breastfeed while you're on levothyroxine. Thyroid hormones pass into breast milk in very low levels that are too small to affect the baby. If you're breastfeeding, it's important that you continue to take levothyroxine.
Your body needs good levels of thyroid hormones to make enough breast milk to feed your baby. Some medicines can interfere with thyroid hormones, so the dose of levothyroxine may need to be changed.
They include:. Levothyroxine can change how other medicines work, so their doses may need to be altered.
These medicines include:. Some medicines should not be taken at the same time of day as levothyroxine as they can reduce the amount of levothyroxine your body takes in, including:. Read the information leaflet supplied with these medicines or speak to your pharmacist for advice on how much time to leave between taking these medicines and taking levothyroxine. There's very little information about taking herbal remedies and supplements with levothyroxine.
Tell your doctor or pharmacist if you're taking any other medicines, including herbal medicines, vitamins or supplements. The thyroid gland in your neck makes a hormone called thyroxine. Thyroxine controls how much energy your body uses the metabolic rate. It's also involved in digestion, how your heart and muscles work, brain development and bone health. When the thyroid gland does not make enough thyroxine called hypothyroidism , many of the body's functions slow down.
Some of the most common symptoms of an underactive thyroid gland are:. Levothyroxine is a synthetic version of thyroxine. You take levothyroxine tablets to replace the thyroxine that your thyroid gland cannot produce and prevent the symptoms of hypothyroidism. Levothyroxine starts working straight away, but it may be several weeks before your symptoms start to improve and you feel any different.
Treatment with levothyroxine is usually lifelong. If you stop taking levothyroxine your symptoms are likely to come back. Yes, it's safe to take levothyroxine for a long time, even many years. High doses of levothyroxine over a long time can sometimes cause weakening of the bones osteoporosis. This should not happen if you are on the right dose. It's important to have regular blood tests to make sure your dose is not too high. There's no clear evidence to suggest that taking levothyroxine will reduce fertility in either men or women.
However, speak to a pharmacist or your doctor if you're trying to get pregnant. They may want to review your treatment. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Do not double doses. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Use the oral liquid within 15 days after opening the pouch. Keep the ampules in the pouch until you are ready to use them.
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